What changed, and what people actually did.

1. Oct 18, 2026 · Release

   Google releases PaperBanana

   Methods text in, a draft figure out. Free. Source

2. Oct 15, 2026 · Release

   Anthropic opens STEM Fellows

   Four months at Anthropic from January 2027, helping Claude reason about hard science problems. Applications close October 28. Source

3. Oct 12, 2026 · Someone did this

   Vicena AI wins the Claude Community Impact Challenge

   Mehdi Farza's team wants designing a drug or a battery to be as simple as building an app. Source

4. Oct 11, 2026 · Release

   Meta funds an open brain dataset

   $15M for 15,000 hours of brain recordings from 100 people, planned as open source. Source

5. Oct 11, 2026 · Release

   NSF and DOE put $100M+ into autonomous labs

   Money for AI-enabled instruments and self-driving labs. Watch for calls you can apply to. Source

6. Oct 7, 2026 · Release

   A $1.8B push for open, AI-ready biology data

   Biohub, DOE, NIH, Meta, Google DeepMind and Isomorphic Labs. The data layer your models will train on. Source

7. Oct 7, 2026 · Release

   Evidence API launches

   Evidence for and against a claim, from 100M+ papers. Source

1. Sep 23, 2026 · Someone did this

   Claude finds an unknown enzyme system in phage DNA

   It sits next to a CRISPR-like repeat array. Anthropic says what it does is not yet known. Source

2. Sep 23, 2026 · Release

   A biology benchmark is patched after agents gamed it

   Agents looked up benchmark identities and invented contact details. Scores fell after the fix. Read benchmark claims with this in mind. Source

3. Sep 19, 2026 · Someone did this

   A model finds one experiment run 1,400 times

   Pointed at 40 years of ribosome methods sections, it flagged results only one lab had ever reported. Per a third-party post. Source

4. Sep 18, 2026 · Release

   Anthropic opens its Life Sciences Verification Program

   Verified labs and companies can apply for fuller access to Claude for biology work. Source

5. Sep 17, 2026 · Someone did this

   Claude makes 30 open bio models 4x faster

   Anthropic open sourced the optimization code. Cheaper runs on the models your team already uses. Source

6. Sep 16, 2026 · Release

   Novo Nordisk partners with Anthropic

   A large pharma company signs on so its scientists can use AI to bring medicines to patients faster. Source

7. Sep 9, 2026 · Someone did this

   Antibodies designed by an AI harness, then tested

   Will Hua's opendde-harness designs antibodies from a plain request. The designs went to the lab. Source

8. Sep 7, 2026 · Someone did this

   A community funds an N-of-1 proteome study

   Andy Hung at Stanford Medicine reached his goal on ResearchHub after 9 public expert reviews. Source

9. Sep 6, 2026 · Someone did this

   A free flow cytometry app

   Jonas Koeppel built Cytofeather with Codex and Claude Code. Source

10. Sep 4, 2026 · Someone did this

    A lab builds its own analysis software

    Derya Unutmaz is building flow cytometry software with GPT-6 Astra to replace paid licenses. Source

11. Sep 3, 2026 · Release

    WeatherNext 3

    Hourly, high-resolution global forecasts, anywhere on Earth through Weather Lab. Source

1. Aug 28, 2026 · Release

   Rosalind Workbench in Codex

   A biology workbench inside a coding agent. Source

2. Aug 27, 2026 · Release

   Terminal-Bench-Science

   70 research tasks. The best model solved about 30%. A useful check on agent claims. Source

3. Aug 25, 2026 · Release

   Adaptyv raises $40M for an automated lab

   Claude-designed proteins went to Adaptyv's wet lab and came back with real data. Source

4. Aug 19, 2026 · Someone did this

   Claude designs protein binders with up to 35% hit rates

   With Adaptyv Bio and Twist Bioscience, binders for 14 of 15 targets. A human expert wrote the 30k-token prompt. Source

5. Aug 19, 2026 · Release

   ICON builds Claude into clinical trials

   A large CRO plans to use it for site selection, enrollment forecasting and protocol design. Per a third-party post. Source

6. Aug 11, 2026 · Release

   OSF Projects to go read-only in February 2027

   Preprints and preregistration stay. If your lab keeps materials on OSF, plan the move. Source

7. Aug 5, 2026 · Release

   Ginkgo builds four autonomous labs at universities

   At MIT, Caltech, Northwestern and Maryland. Source

1. Jul 20, 2026 · Someone did this

   Dead research code brought back

   Dean Sherry's Lazarus agent revives broken bioinformatics repos. It won a Claude life science hackathon. Source

1. Oct 15, 2026 · Policy

   Commission launches RAISE pledging initiative

   Dublin summit; first pledgers include Elsevier, Google, Mistral AI, Novo Nordisk Foundation, NVIDIA and Sanofi. Source

2. Oct 8, 2026 · Autonomous labs

   DOE funds four national lab autonomous discovery projects

   SLAC, Argonne, Brookhaven and Oak Ridge will build self-driving lab tools with $30M, only $2M funded for FY2026. Source

3. Oct 8, 2026 · Math

   AlphaProof Nexus published in Science

   Science paper reports Lean-verified proofs for 9 of 353 Erdos problems and 44 of 492 OEIS conjectures. Source

4. Sep 25, 2026 · Physics

   Claude computes nine-loop N=4 super Yang-Mills amplitude

   Claude computed the nine-loop MHV six-particle amplitude in planar N=4 super Yang-Mills; Lance Dixon validated it. Source

5. Sep 1, 2026 · Policy

   NSF awards NAIRR Operations Center to UC San Diego

   NSF award to the San Diego Supercomputer Center, with TACC as collaborator, for the NAIRR Operations Center. Source

6. Aug 20, 2026 · Biology

   Arc launches 2026 Virtual Cell Challenge

   Second edition tests zero-shot prediction of CRISPRi responses in six cell lines never seen; $100k grand prize. Source

7. Jul 22, 2026 · Policy

   White House announces $5B+ in Genesis Mission commitments

   More than $5B in federal commitments from 15+ agencies; DOE says 278 projects were selected. Source

8. Jul 14, 2026 · Institutions and money

   Chai Discovery raises $400M Series C at $3.8B valuation

   Round for AI molecule and antibody design; Index Ventures led. Source

9. Jul 8, 2026 · Weather and climate

   Met Office and Turing present FastNet AI weather model

   FastNet matches the Met Office Global Model on key metrics with sharper storms, but is not yet operational. Source

10. Jul 7, 2026 · Drugs

    Insilico starts Phase 3 trial of rentosertib in IPF

    Insilico says AI found the target and designed the drug; Phase 3 enrolls about 320 patients in China. Source

11. Jun 30, 2026 · Institutions and money

    Anthropic launches Claude Science workbench

    Beta workbench with 60+ skills and connectors, HPC and Modal job control, and up to $30k credits for 50 science projects. Source

12. Jun 25, 2026 · Imaging

    Aidoc First Read gets FDA Breakthrough designation

    Designation for AI that drafts preliminary chest X-ray report text; investigational and not FDA cleared. Source

13. Jun 11, 2026 · Drugs

    Takeda zasocitinib beats deucravacitinib in Phase 3 head-to-head

    Topline LATITUDE Atlas: zasocitinib beat deucravacitinib on PASI 100 at week 16 in 606 patients; company-reported. Source

14. Jun 8, 2026 · Neuroscience

    Complete fly brain and nerve cord connectome in Nature

    Nature paper maps all neurons in an adult fly's brain and nerve cord; AI tools aligned the electron microscopy images. Source

15. Jun 4, 2026 · Policy

    Japan and US sign Genesis Mission AI for Science partnership

    MEXT, METI and DOE signed a Statement of Intent making Japan the first international Genesis partner. Source

16. May 21, 2026 · Math

    AlphaProof Nexus preprint: 9 Erdos problems, 44 OEIS conjectures

    Lean-based agent resolved 9 of 353 open Erdos problems and 44 of 492 OEIS conjectures, at a few hundred dollars per problem. Source

17. May 20, 2026 · AI scientists

    Mathematicians verify OpenAI Erdos unit distance counterexample

    Nine mathematicians incl. Alon and Gowers wrote a human-verified companion note on OpenAI's counterexample; arXiv preprint. Source

18. May 12, 2026 · Weather and climate

    ECMWF AIFS v2 adds wave and snow-cover forecasts

    ECMWF's first data-driven wave and snow cover forecasts went live on 12 May 2026 with AIFS v2. Source

19. May 12, 2026 · Institutions and money

    Isomorphic Labs raises $2.1B Series B

    Thrive-led round with Alphabet, GV, MGX, Temasek, CapitalG and the UK Sovereign AI Fund. Source

20. May 5, 2026 · Neuroscience

    TRIBE v2: in-silico brain model for vision, audio, language

    Preprint: one model predicts human fMRI from video, audio and text, trained on 720 subjects; reproduces classic findings. Source

21. May 5, 2026 · Materials

    Autonomous lab finds brighter lead-free nanomaterials in 12 hours

    PoLARIS self-driving lab ran 120 experiments in 12 hours and found brighter lead-free perovskite nanoplatelets (Nature Communications). Source

22. May 1, 2026 · Math

    Erdos problem 1196 solved with GPT-5.4 Pro and Terence Tao

    Paper with Tao proves Erdos #1196 using a method suggested by GPT-5.4 Pro; a hobbyist prompted the model. Source

23. Apr 29, 2026 · Institutions and money

    Biohub commits $500M to Virtual Biology Initiative

    A five-year plan to generate open data and tools for predictive models of the cell. Source

24. Apr 28, 2026 · Policy

    CAS unveils ScienceOne 100 across 50+ institutes

    The ScienceOne system added eight domain models and 2,000+ research tools used in over 100 research scenarios. Source

25. Mar 26, 2026 · AI scientists

    Sakana's AI Scientist published in Nature

    Nature paper covers the system and scaling results; its automated reviewer reached 69% balanced accuracy. Source

26. Mar 10, 2026 · AI scientists

    AlphaEvolve improves nine classical Ramsey lower bounds

    Google researchers used AlphaEvolve to raise lower bounds for nine Ramsey numbers, e.g. R(3,13) from 60 to 61; preprint. Source

27. Mar 4, 2026 · Genomics

    Evo 2 published in Nature

    Peer-reviewed publication of the open Evo 2 genome model, "Genome modelling and design across all domains of life". Source

28. Feb 25, 2026 · Astronomy

    Rubin Observatory launches real-time public alerts

    About 800,000 alerts the first night, up to 7M a night planned, filtered by community brokers using ML. Source

29. Feb 20, 2026 · Institutions and money

    Gates, Novo and Wellcome launch $60M EVAH health AI fund

    The funders will pay for local evaluations of AI health tools in low- and middle-income countries. Source

30. Feb 2, 2026 · Materials

    MIT DiffSyn proposes synthesis routes for new zeolites

    Diffusion model trained on 23,000+ recipes proposes zeolite synthesis routes; the team made a new, more heat-stable zeolite. Source

31. Jan 22, 2026 · Institutions and money

    Gates, Novo and Wellcome fund $60M AI antibiotic discovery

    Three funders put $60M over three years into antibiotic discovery projects using AI-enabled models. Source

32. Jan 20, 2026 · Autonomous labs

    ARIA funds 12 AI scientist projects to run their own experiments

    The UK agency backed teams building systems that plan, run and analyze experiments end to end. Source

33. Jan 6, 2026 · Math

    Aristotle and GPT-5.2 Pro solve Erdos problem 728 in Lean

    Lean-verified proof of Erdos #728 by Harmonic's Aristotle with GPT-5.2 Pro; a writeup calls it the first resolved autonomously by AI. Source

1. Dec 17, 2025 · Weather and climate

   NOAA deploys AIGFS, AIGEFS and HGEFS operationally

   NOAA made its AI global model (AIGFS), AI ensemble (AIGEFS) and hybrid ensemble (HGEFS) operational. Source

2. Dec 10, 2025 · Autonomous labs

   DeepMind plans UK automated materials lab in 2026

   UK partnership includes a Gemini-integrated lab to synthesize and characterize hundreds of materials a day, opening in 2026. Source

3. Dec 6, 2025 · Biology

   Arc Virtual Cell Challenge 2025 wrap-up: 5,000+ registrants

   Over 5,000 registered from 114 countries; 1,200+ teams submitted and 300+ made final submissions. Source

4. Nov 25, 2025 · Proteins

   AlphaFold at five years: 3M+ researchers use AlphaFold DB

   DeepMind says the AlphaFold Protein Database has been used by over 3 million researchers in more than 190 countries. Source

5. Nov 24, 2025 · Physics

   Genesis Mission executive order launches US AI-for-science push

   Executive Order 14363 directs DOE to build an American Science and Security Platform for AI-driven science. Source

6. Nov 20, 2025 · Policy

   UK publishes AI for Science Strategy with 15 actions

   DSIT set out how the UK will use AI for discovery, including AI-ready lab data and science missions. Source

7. Nov 17, 2025 · Weather and climate

   WeatherNext 2 released

   Google says WeatherNext 2 is 8x faster and beats its prior model on 99.9% of variables; data via Earth Engine and BigQuery. Source

8. Nov 12, 2025 · Math

   AlphaProof paper published in Nature

   Nature paper describes the RL system behind the IMO 2024 silver-level result; it solved 4 of 6 problems with AlphaGeometry. Source

9. Nov 5, 2025 · Proteins

   Baker lab publishes de novo antibody design with RFdiffusion

   Nature paper reports RFdiffusion fine-tuned to design antibodies de novo with atomic accuracy. Source

10. Nov 4, 2025 · AI scientists

    Edison Scientific releases Kosmos AI scientist preprint

    Preprint reports seven discoveries across four fields from 20-cycle runs; four described as novel, three reproduced unpublished work. Source

11. Nov 3, 2025 · Policy

    EU launches RAISE pilot under its AI in Science strategy

    Commission launched the RAISE pilot (EUR 107M, Horizon Europe) as flagship of its European Strategy for AI in Science. Source

12. Oct 22, 2025 · AI scientists

    Agents4Science: first conference with AI authors and reviewers

    Stanford-run online conference where AI systems were primary authors and reviewers of papers. Source

13. Oct 20, 2025 · Institutions and money

    Anthropic launches Claude for Life Sciences

    Adds connectors to Benchling, BioRender, PubMed, Scholar Gateway, Synapse.org and 10x Genomics. Source

14. Oct 15, 2025 · Lab methods

    Google C2S-Scale 27B predicts a cancer immunotherapy lead

    Cell2Sentence model predicted silmitasertib; with low-dose interferon it raised antigen presentation about 50% in cell models. Source

15. Oct 8, 2025 · Policy

    EU adopts European Strategy for AI in Science with RAISE

    The Commission set up a virtual institute plan, 600M euros for compute access and a goal to double AI funding. Source

16. Sep 30, 2025 · Materials

    Periodic Labs launches with $300M seed

    Ex-OpenAI and DeepMind founders began an AI-scientist lab for physical science with autonomous labs. Source

17. Sep 17, 2025 · Genomics

    Evo-designed bacteriophage genomes generated and tested

    Arc and Stanford used Evo to design viable phage genomes, which Arc calls the first AI-generated genomes. Source

18. Sep 3, 2025 · Neuroscience

    International Brain Laboratory brain-wide map of decision making

    IBL recorded over 600,000 neurons across 12 labs with standardized pipelines. Source

19. Sep 2, 2025 · Institutions and money

    OpenAI for Science group formed under Kevin Weil

    OpenAI set up a dedicated unit to build tools for scientific discovery. Source

20. Sep 2025 · Astronomy

    Deep Loop Shaping cuts LIGO control noise 30x or more

    A DeepMind reinforcement-learning controller cut LIGO control noise by over 30 times in the 10 to 30 Hz band. Source

21. Aug 26, 2025 · Policy

    China State Council issues AI Plus plan with science as first field

    The plan puts AI-driven scientific research first among six fields for national AI adoption. Source

22. Aug 14, 2025 · Institutions and money

    NSF and NVIDIA give Ai2 $152M for open science AI models

    NSF and NVIDIA funded the OMAI project to build fully open AI models for scientific discovery. Source

23. Aug 14, 2025 · Neuroscience

    Inner speech decoded from motor cortex

    Kunz et al. decoded imagined sentences at up to 74% accuracy with a privacy password safeguard. Source

24. Aug 14, 2025 · Medicine

    Generative AI designs antibiotics against gonorrhea and MRSA

    Krishnan et al. designed compounds from scratch rather than screening known libraries. Source

25. Jul 30, 2025 · Earth

    AlphaEarth Foundations embedding field for the planet

    Google DeepMind released annual 10 metre embeddings from many satellite sources for mapping. Source

26. Jul 26, 2025 · Policy

    CAS unveils ScienceOne scientific foundation model

    The Chinese Academy of Sciences released a model that reads spectra and waveforms and orchestrates science tools. Source

27. Jul 21, 2025 · Math

    Gemini Deep Think and OpenAI model earn IMO gold in natural language

    Both labs solved 5 of 6 IMO 2025 problems, 35 of 42, in plain English; DeepMind's was IMO-certified. Source

28. Jul 17, 2025 · Policy

    Isambard-AI officially opens as UK's top AI research machine

    The 225M pound Bristol system opened to researchers as part of the AI Research Resource. Source

29. Jul 7, 2025 · Drugs

    Isomorphic Labs says first human trials are very close

    President Colin Murdoch told Fortune the firm was staffing up and getting very close to first human trials of AI-designed drugs. Source

30. Jul 1, 2025 · Weather and climate

    ECMWF AIFS ensemble goes operational

    51-member probabilistic AI ensemble (AIFS-CRPS) released operationally 1 July 2025. Source

31. Jul 2025 · Policy

    UK Compute Roadmap commits up to 2B pounds, AIRR 20x by 2030

    The UK pledged 1B+ pounds to grow its AI Research Resource twentyfold and 750M pounds for an Edinburgh supercomputer. Source

32. Jun 27, 2025 · Medicine

    Microsoft MAI-DxO diagnostic orchestrator

    Microsoft reported its diagnostic orchestrator solved most hard NEJM cases, far above unaided physicians, in a simulated setting. Source

33. Jun 26, 2025 · Institutions and money

    Arc Institute launches Virtual Cell Challenge

    Public competition to predict cell responses to perturbation, with Nvidia and 10x as sponsors. Source

34. Jun 25, 2025 · Genomics

    DeepMind releases AlphaGenome

    One model predicts regulatory effects of variants across 1Mb of DNA. Source

35. Jun 23, 2025 · Astronomy

    Rubin Observatory first images; ML alert brokers prepared

    First look images released 23 June 2025; LSST alerts rely on ML brokers. Source

36. Jun 23, 2025 · Lab methods

    Arc Institute releases State virtual cell model

    State predicts cell responses to perturbation; released three days before the Virtual Cell Challenge launched. Source

37. Jun 12, 2025 · Neuroscience

    Instantaneous voice synthesis from motor cortex

    Wairagkar et al. synthesized a participant's own voice in about 25 ms with intonation. Source

38. Jun 12, 2025 · Weather and climate

    Google Weather Lab and cyclone model shared with NHC

    DeepMind opened an experimental cyclone model, tested live with the US National Hurricane Center. Source

39. Jun 6, 2025 · Drugs

    Boltz-2 predicts structure and binding affinity

    Open model from MIT and Recursion approached FEP accuracy at up to 1000x the speed. Source

40. Jun 3, 2025 · Drugs

    Insilico rentosertib Phase 2a result published in Nature Medicine

    Insilico AI-discovered target and AI-designed molecule showed lung function gains in a randomized phase 2a IPF trial. Source

41. May 27, 2025 · AI scientists

    Zochi paper accepted at ACL 2025 main conference

    Intology says an AI-authored paper cleared main-track review at a top NLP venue. Source

42. May 19, 2025 · Materials

    Microsoft Discovery platform announced

    Agentic R&D platform whose agents found a coolant candidate in 200 hours, which was then synthesised. Source

43. May 19, 2025 · AI scientists

    FutureHouse Robin agent proposes ripasudil for dry AMD

    Multi-agent system Robin proposed ripasudil as a dry AMD candidate, then lab-tested it; arXiv preprint. Source

44. May 14, 2025 · AI scientists

    AlphaEvolve improves algorithms and math bounds

    Gemini coding agent found faster matrix multiplication and recovered Google compute savings. Source

45. May 6, 2025 · Astronomy

    AnomalyMatch scans 99.6M Hubble cutouts for oddities

    An AI ranked the Hubble Legacy Archive in 2-3 days, surfacing 138 new lens candidates and 417 mergers. Source

46. May 5, 2025 · Institutions and money

    Anthropic launches AI for Science program

    API credits for academic and nonprofit researchers, the first step of Anthropic's science push. Source

47. Apr 9, 2025 · Neuroscience

    MICrONS: mouse visual cortex wired and recorded at cubic-mm scale

    Function and structure of 200,000 cells linked, with a foundation model of cortex in the companion paper. Source

48. Apr 9, 2025 · Medicine

    AMIE conversational diagnostic AI beats physicians in blinded study

    Google's Articulate Medical Intelligence Explorer outperformed primary care doctors on text-based consults. Source

49. Mar 31, 2025 · Institutions and money

    Isomorphic Labs raises first external round of $600M

    Alphabet's AI drug design spinout took outside capital for the first time. Source

50. Mar 19, 2025 · Astronomy

    Euclid Q1 opens with ML-led strong lens search

    Euclid's first release found 497 lens candidates; a fine-tuned Zoobot topped five ML models. Source

51. Mar 17, 2025 · Earth

    First FireSat satellite launches for AI wildfire detection

    Google-backed FireSat aims to spot classroom-sized fires with global imagery every 20 minutes. Source

52. Mar 12, 2025 · AI scientists

    Sakana's AI Scientist v2 paper passes workshop review

    First fully AI-generated paper accepted at an ICLR 2025 workshop, then withdrawn by design. Source

53. Mar 10, 2025 · Institutions and money

    Lila Sciences emerges with $200M seed

    Flagship Pioneering launched an 'scientific superintelligence' company tied to autonomous labs. Source

54. Feb 25, 2025 · Biology

    Arc releases Virtual Cell Atlas with 300M+ cells

    Largest open single-cell compendium for virtual cell models. Source

55. Feb 25, 2025 · Lab methods

    Tahoe-100M single-cell perturbation atlas

    100 million cell perturbation dataset aimed at training virtual cell models. Source

56. Feb 25, 2025 · Weather and climate

    ECMWF AIFS becomes operational

    First fully operational ML global model at a major forecasting centre, 25 Feb 2025. Source

57. Feb 19, 2025 · AI scientists

    Google unveils AI co-scientist

    Gemini-based multi-agent system that proposes and ranks hypotheses, with lab-validated results. Source

58. Feb 19, 2025 · Genomics

    Evo 2 released: 40B-parameter genome model

    Trained on 9.3T nucleotides across all life, with open weights and variant effect prediction. Source

59. Feb 18, 2025 · Neuroscience

    Brain2Qwerty decodes typed sentences from non-invasive MEG

    Meta AI showed sentences reconstructed from brain activity without surgery. Source

60. Feb 3, 2025 · Imaging

    Large mammography AI trial: 29% more cancers found

    MASAI randomized trial: AI-supported screening detected 29% more cancers with a substantially lower reading workload. Source

61. Feb 2, 2025 · AI scientists

    OpenAI launches Deep Research

    Agent that produces multi-page research reports, mainstreaming agentic literature work. Source

62. Jan 24, 2025 · AI scientists

    Humanity's Last Exam released

    Expert-written benchmark became the standard stress test for frontier model reasoning on science. Source

63. Jan 16, 2025 · Materials

    MatterGen generative model for inorganic materials

    Microsoft's diffusion model designed new stable materials to target properties, one synthesised. Source

1. Dec 11, 2024 · AI scientists

   Google launches Gemini Deep Research

   Early agentic research product that reads many web sources and writes cited reports. Source

2. Dec 10, 2024 · Policy

   EuroHPC selects first seven AI Factories

   Europe picked seven sites to host AI supercomputers open to researchers, startups and industry. Source

3. Dec 5, 2024 · Earth

   Samudra AI ocean emulator runs 150x faster

   A 3D global ocean emulator stayed stable for centuries and ran 150 times faster than the source ocean model. Source

4. Dec 4, 2024 · Weather and climate

   GenCast probabilistic ensemble outperforms ENS

   DeepMind diffusion model beat ECMWF's ensemble on 97 percent of targets, 15-day ensembles in 8 minutes. Source

5. Dec 3, 2024 · Earth

   Prithvi-EO-2.0 open Earth observation foundation model

   NASA and IBM released an open multi-temporal model that beat Prithvi-EO-1.0 by 8 percent on GEO-Bench. Source

6. Nov 20, 2024 · Drugs

   Recursion completes Exscientia merger in AI drug discovery

   Combined company pooled phenomics and generative chemistry platforms. Source

7. Nov 18, 2024 · Weather and climate

   Ai2 ACE2 reproduces 80 years of atmospheric variability

   A 450M-parameter emulator tracked variability from days to decades, though forced responses were imperfect. Source

8. Nov 18, 2024 · Medicine

   TrialGPT matches patients to clinical trials

   Jin et al. showed LLM matching approaches expert accuracy and cuts screening time. Source

9. Nov 11, 2024 · Proteins

   AlphaFold 3 code and weights released for academic use

   Code released openly; weights on request for academic non-commercial use, after criticism of the server-only May 2024 release. Source

10. Oct 28, 2024 · Physics

    CaloChallenge 2022 benchmarks 31 fast calorimeter simulators

    A community challenge compared GANs, flows and diffusion models for shower simulation. Source

11. Oct 9, 2024 · Proteins

    Nobel Chemistry awarded to Baker, Hassabis and Jumper

    The Nobel recognised computational protein design and AlphaFold structure prediction. Source

12. Oct 8, 2024 · Physics

    Nobel Prize in Physics for neural network foundations

    Hopfield and Hinton won for foundational discoveries enabling machine learning with artificial neural networks. Source

13. Oct 2, 2024 · Neuroscience

    FlyWire: first whole adult fly brain connectome

    Dorkenwald and Schlegel et al. released 139,255 neurons and 50 million synapses, proofread by humans and AI. Source

14. Aug 14, 2024 · Neuroscience

    Speech neuroprosthesis reaches up to 97% accuracy

    Card et al. gave a man with ALS near-natural speech decoding: 97.5% word accuracy at 8 months, one participant. Source

15. Aug 12, 2024 · Institutions and money

    HHMI commits $500M over 10 years to AI@HHMI

    HHMI centered a decade-long AI program at Janelia and funded AI-in-the-loop experiments across its labs. Source

16. Aug 12, 2024 · AI scientists

    Sakana releases The AI Scientist

    First end-to-end system that ideates, codes, runs and writes up ML papers for about $15 each. Source

17. Aug 1, 2024 · Policy

    CSIRO and Google expand collaboration on AI for science

    Australia's national science agency and Google agreed to speed AI use across Australian research. Source

18. Jul 25, 2024 · Math

    AlphaProof and AlphaGeometry 2 reach IMO silver level

    DeepMind solved 4 of 6 IMO 2024 problems, scoring 28 of 42, with Lean-verified proofs. Source

19. Jul 22, 2024 · Medicine

    Virchow foundation model for cancer pathology

    Vorontsov et al. showed a model trained on 1.5 million slides detecting rare cancers at pan-cancer level. Source

20. Jul 22, 2024 · Weather and climate

    NeuralGCM hybrid climate model

    Google's differentiable hybrid model matched weather skill and ran decades of climate simulation. Source

21. Jul 16, 2024 · Policy

    DOE publishes FASST roadmap for AI in science and security

    DOE and its 17 labs set out a plan for AI-ready data, AI supercomputers and foundation models. Source

22. Jul 14, 2024 · AI scientists

    LAB-Bench measures LLM biology research skills

    FutureHouse benchmark for literature, protocol and sequence tasks became a reference for science agents. Source

23. Jun 25, 2024 · Proteins

    EvolutionaryScale launches ESM3 with 142M seed round

    ESM3 generated a new fluorescent protein 500M years of evolution away from known ones. Source

24. Jun 10, 2024 · Weather and climate

    Destination Earth enters phase 2 at LUMI

    EU digital twin programme moved toward operations with km-scale Climate and Extremes twins and more machine learning. Source

25. May 22, 2024 · Medicine

    Prov-GigaPath whole-slide pathology foundation model

    Xu et al. trained on 1.3 billion tiles from 171,000 slides across Providence health system. Source

26. May 20, 2024 · Weather and climate

    Aurora foundation model for the Earth system

    Microsoft's 1.3B parameter model outperformed operational systems on weather, air quality and waves. Source

27. May 10, 2024 · Policy

    Japan releases Fugaku-LLM trained on the Fugaku supercomputer

    A 13B Japanese language model was trained on CPU-based Fugaku and released openly. Source

28. May 10, 2024 · Neuroscience

    H01: petabyte human cortex connectome

    Shapson-Coe et al. reconstructed a cubic millimeter of human temporal cortex with 57,000 cells and 150 million synapses. Source

29. May 8, 2024 · Proteins

    AlphaFold 3 predicts all biomolecular interactions

    Diffusion model modelled proteins, DNA, RNA, ligands and ions together, beating docking tools. Source

30. Apr 23, 2024 · Institutions and money

    Xaira Therapeutics launches with over $1 billion

    One of the largest AI biotech launches, built around protein and generative design. Source

31. Mar 20, 2024 · Earth

    Google AI flood forecasting extends to 80 countries (Nature)

    Global river flood forecasting models gave reliable 7-day warnings in ungauged basins. Source

32. Mar 19, 2024 · Medicine

    UNI general-purpose pathology foundation model

    Mahmood lab released UNI, a self-supervised model that generalizes across dozens of pathology tasks. Source

33. Mar 18, 2024 · Weather and climate

    NVIDIA unveils Earth-2 and CorrDiff at GTC

    NVIDIA launched a cloud climate digital twin platform with a generative km-scale downscaling model. Source

34. Mar 2024 · Earth

    MethaneSAT launches to map oil and gas methane

    EDF's satellite targeted global oil and gas methane emissions from space before contact was lost in June 2025. Source

35. Feb 27, 2024 · Genomics

    Evo introduced: DNA foundation model at single-nucleotide resolution

    Arc/Stanford's Evo modeled bacterial and phage genomes at 131kb context and designed CRISPR systems. Source

36. Feb 26, 2024 · Lab methods

    scGPT: generative pretrained model for single cell

    Cui et al. trained a transformer on over 33 million cells for annotation and perturbation prediction. Source

37. Feb 21, 2024 · Physics

    AI predicts tokamak tearing instabilities ahead of time

    Princeton and Seoul team's model predicted tearing modes in DIII-D and avoided them. Source

38. Jan 29, 2024 · Neuroscience

    Neuralink implants first human participant

    Musk announced the first human implant in the PRIME trial of a wireless BCI (implant on Jan 28). Source

39. Jan 24, 2024 · Policy

    NAIRR pilot launched by NSF

    US pilot gave researchers shared access to compute, models and data from federal and private partners. Source

40. Jan 22, 2024 · Imaging

    MedSAM: segment anything for medical images

    Ma et al. adapted a foundation segmentation model to 10 imaging modalities. Source

41. Jan 17, 2024 · Math

    AlphaGeometry solves olympiad geometry near gold level

    Neuro-symbolic system solved 25 of 30 IMO geometry problems, close to a gold medallist. Source

42. Jan 8, 2024 · Materials

    Microsoft and PNNL AI screens 32M candidates, new battery electrolyte

    Azure Quantum Elements pipeline screened about 32M candidates to a solid-state electrolyte that was synthesized and tested. Source

43. Jan 7, 2024 · Drugs

    Isomorphic Labs signs Lilly and Novartis drug discovery deals

    Up to $2.9B in milestones plus about $82.5M upfront across the Lilly and Novartis collaborations. Source

1. Dec 29, 2023 · Materials

   MACE-MP-0 universal ML interatomic potential

   A foundation interatomic potential covering much of the periodic table, trained on Materials Project data. Source

2. Dec 20, 2023 · Autonomous labs

   Coscientist plans and runs chemistry with GPT-4

   An LLM agent designed, coded and executed real reactions on lab hardware. Source

3. Dec 20, 2023 · Medicine

   AI discovers a new structural class of antibiotics

   Wong et al. used explainable deep learning to find compounds active against MRSA. Source

4. Dec 15, 2023 · Physics

   CMS tests anomaly-detection autoencoder in Level-1 test crate

   An autoencoder ran on real collision data in a test copy of the CMS Global Trigger before going live. Source

5. Dec 14, 2023 · AI scientists

   FunSearch finds new math results with an LLM

   An LLM plus evaluator loop found new cap set constructions, a first for LLM-led open problems. Source

6. Dec 13, 2023 · Neuroscience

   Whole mouse brain cell type atlas

   Yao et al. (Allen Institute) mapped over 5,300 cell types using ML clustering on 4 million cells. Source

7. Nov 29, 2023 · AI scientists

   GNoME predicts 2.2 million new crystals

   DeepMind's graph network expanded known stable materials by an order of magnitude. Source

8. Nov 29, 2023 · Autonomous labs

   A-Lab synthesizes 41 new inorganic materials

   An autonomous lab reported making 41 of 58 target compounds in 17 days. Source

9. Nov 15, 2023 · Proteins

   Chroma generative protein model published in Nature

   Programmable diffusion model Chroma designed proteins, with experimental validation. Source

10. Nov 14, 2023 · Weather and climate

    GraphCast beats HRES on 90 percent of targets

    DeepMind's graph network gave 10-day forecasts in under a minute on one chip. Source

11. Nov 1, 2023 · Policy

    UK commits 225M pounds to Isambard-AI under new AI Research Resource

    The UK announced a Bristol AI supercomputer within a 300M pound national AI Research Resource. Source

12. Oct 9, 2023 · Institutions and money

    Simons and Flatiron launch Polymathic AI science models

    A multi-institution team began building one model that learns from simulations across many scientific fields. Source

13. Oct 4, 2023 · Astronomy

    AstroCLIP cross-modal foundation model for galaxies

    AstroCLIP aligns galaxy images and spectra; AstroLLaMA (arXiv 2023-09-12) was an earlier astronomy LLM. Source

14. Oct 3, 2023 · Weather and climate

    Ai2 ACE emulates a 100 km atmosphere model

    A 200M-parameter emulator stayed stable for 100 years and ran about 100 times faster than its source model. Source

15. Sep 24, 2023 · Weather and climate

    CorrDiff diffusion model downscales weather to 2 km

    A diffusion model downscaled 25 km data to 2 km over Taiwan, cheaply adding km-scale detail. Source

16. Sep 19, 2023 · Institutions and money

    Chan Zuckerberg Initiative builds 1,000+ GPU cluster for cell models

    CZI funded a nonprofit GPU cluster to train open predictive models of healthy and diseased cells. Source

17. Sep 19, 2023 · Genomics

    AlphaMissense classifies 71M human missense variants

    Predicted pathogenicity for nearly all missense variants, a resource for rare disease genetics. Source

18. Sep 13, 2023 · Medicine

    RETFound foundation model for retinal images

    Zhou et al. trained on 1.6 million retinal images and transferred to eye and systemic disease prediction. Source

19. Aug 28, 2023 · Materials

    Matbench Discovery benchmark for ML materials stability

    Benchmark ranking universal potentials on finding stable crystals shaped the field's evaluation. Source

20. Aug 24, 2023 · Physics

    ATLAS unsupervised autoencoder anomaly search

    ATLAS applied unsupervised ML to Run 2 data, called a first at a collider, with a 2.9 sigma top excess. Source

21. Aug 23, 2023 · Neuroscience

    Speech BCIs reach 62 and 78 words per minute

    Willett and Metzger papers decoded speech, with an avatar in Metzger, at far higher rates than before. Source

22. Aug 3, 2023 · Earth

    Prithvi geospatial foundation model (NASA and IBM)

    Open foundation model on satellite imagery for flood, burn scar and land mapping. Source

23. Jul 12, 2023 · Medicine

    Med-PaLM passes USMLE-style medical questions

    Singhal et al. showed an LLM passing USMLE-style questions with physician-rated answer quality. Source

24. Jul 11, 2023 · Proteins

    RFdiffusion enables de novo binders and enzymes

    Diffusion-based design produced working binders, symmetric assemblies and motifs at high success rates. Source

25. May 31, 2023 · Lab methods

    Geneformer: transfer learning for network biology

    First widely used single-cell foundation model, pretrained on about 30 million cells. Source

26. May 25, 2023 · Medicine

    Abaucin: AI finds an antibiotic against Acinetobacter

    Liu et al. used ML to find a narrow-spectrum drug for a top-priority resistant pathogen. Source

27. May 24, 2023 · Neuroscience

    Digital bridge restores walking after spinal cord injury

    Lorach et al. linked decoded brain signals to spinal stimulation in a paralyzed man. Source

28. May 4, 2023 · Policy

    NSF funds seven new AI Research Institutes with $140M

    NSF expanded its national AI institutes network to close to half a billion dollars in total investment. Source

29. May 1, 2023 · Neuroscience

    Semantic decoder reconstructs language from fMRI

    Tang et al. decoded the gist of continuous speech noninvasively. Source

30. Apr 28, 2023 · Autonomous labs

    Toronto wins C$200M for Acceleration Consortium self-driving labs

    Canada's largest university research grant funds AI and robotics labs for materials and molecule discovery. Source

31. Apr 13, 2023 · Astronomy

    PRIMO ML sharpens the M87 black hole image

    PRIMO used simulation-trained learned priors to reconstruct a sharper M87 ring from EHT data. Source

32. Apr 11, 2023 · Chemistry

    ChemCrow: LLM chemistry agent with expert tools

    Tool-augmented GPT-4 planned syntheses and guided an insect repellent and organocatalysts. Source

33. Mar 27, 2023 · Policy

    China launches AI for Science deployment via MOST and NSFC

    The science ministry and NSFC started a national push to use AI in basic research, drug work and new materials. Source

34. Mar 20, 2023 · Medicine

    GPT-4 passes medical licensing exam benchmarks

    Nori et al. showed a general LLM exceeding passing scores on USMLE without specialized training. Source

35. Mar 16, 2023 · Proteins

    ESM-2 and ESMFold published in Science

    Language-model-only structure prediction ran much faster than AlphaFold 2 and predicted 600M metagenomic proteins. Source

36. Mar 10, 2023 · Neuroscience

    Complete larval fruit fly connectome

    Winding et al. mapped 3,016 neurons and 548,000 synapses of a whole insect brain. Source

37. Jan 24, 2023 · Weather and climate

    ClimaX foundation model for weather and climate

    A pretrained transformer was fine-tuned for many weather and climate tasks, an early climate foundation model. Source

38. 2023 · Institutions and money

    RIKEN launches TRIP-AGIS platform for AI for Science

    RIKEN built a platform to put AI inside hypothesis generation, modeling and robotic experiments. Source

1. Nov 16, 2022 · AI scientists

   Meta releases Galactica science language model

   Meta released Galactica, a language model trained on scientific text, for science tasks. Source

2. Nov 3, 2022 · Weather and climate

   Pangu-Weather matches ECMWF IFS skill

   Huawei's 3D transformer reported forecasts beating ECMWF IFS on deterministic scores. Source

3. Oct 26, 2022 · Institutions and money

   Schmidt AI in Science Postdocs start at nine universities

   A $148M fellowship funds postdocs who apply AI across the natural sciences at nine universities worldwide. Source

4. Oct 5, 2022 · Math

   AlphaTensor discovers faster matrix multiplication algorithms

   RL found algorithms beating Strassen for 4x4 matrices in a finite field, a 50-year-old record. Source

5. Sep 20, 2022 · Medicine

   EMA qualifies Unlearn PROCOVA covariate adjustment method

   EMA qualified prognostic covariate adjustment, using AI prognostic scores to raise trial power in phase 2 and 3 trials. Source

6. Sep 15, 2022 · Proteins

   ProteinMPNN published in Science

   ProteinMPNN made inverse folding robust, a core tool for AI protein design. Source

7. Sep 2022 · Policy

   NIH launches Bridge2AI to build AI-ready biomedical datasets

   NIH committed $130M over four years so biomedical data can train AI models. Source

8. Jul 28, 2022 · Proteins

   AlphaFold DB expands to 200 million structures

   Nearly every known protein got a predicted structure, a step change in coverage. Source

9. Jun 29, 2022 · Math

   Minerva solves quantitative reasoning problems

   Google's LLM reached over 50 percent on MATH, showing LLMs could do college-level quant reasoning. Source

10. May 4, 2022 · Chemistry

    Equivariant GNNs (NequIP) reach near-DFT accuracy with little data

    E(3)-equivariant networks made data-efficient interatomic potentials practical. Source

11. Feb 22, 2022 · Weather and climate

    FourCastNet global AI weather model

    NVIDIA's Fourier neural operator model forecast fast at 0.25 degree, an early AI-weather proof. Source

12. Feb 21, 2022 · Drugs

    Insilico's INS018_055 enters Phase 1 trial

    Phase 1 of an AI-discovered target and AI-generated molecule began in healthy volunteers. Source

13. Feb 16, 2022 · Physics

    DeepMind and EPFL reinforcement learning controls tokamak plasma

    RL agent shaped plasma on the TCV tokamak, a first for learned fusion control. Source

1. Dec 1, 2021 · Math

   DeepMind AI guides new knot theory and representation theorems

   ML found patterns that led to new theorems in knot invariants and Kazhdan-Lusztig polynomials. Source

2. Nov 19, 2021 · Astronomy

   ExoMiner validates 301 new Kepler exoplanets

   An explainable NASA deep network confirmed 301 planets at 0.936 recall at 99 percent precision. Source

3. Nov 18, 2021 · Imaging

   Mesmer: human-level whole-cell segmentation of tissue

   Greenwald et al. released TissueNet and a model that standardizes multiplexed imaging analysis. Source

4. Nov 1, 2021 · Drugs

   Isomorphic Labs launched as new Alphabet company

   Alphabet formed a dedicated AI drug discovery company built on AlphaFold. Source

5. Sep 22, 2021 · Medicine

   FDA grants De Novo to Paige Prostate AI pathology software

   De Novo grant for software that flags suspected prostate cancer on whole slide images. Source

6. Sep 6, 2021 · Physics

   AtlFast3 uses ML for fast ATLAS calorimeter simulation

   ATLAS replaced the slowest Geant4 calorimeter step with parameterized plus ML simulation. Source

7. Aug 30, 2021 · Autonomous labs

   Carnegie Mellon and Emerald Cloud Lab plan first university cloud lab

   CMU announced a $40M remote-controlled lab with 100+ instruments, the first cloud lab built inside a university. Source

8. Jul 22, 2021 · Proteins

   AlphaFold DB opens with 350,000 structures

   EMBL-EBI hosted predicted structures for the human proteome and 20 model organisms, free to all. Source

9. Jul 15, 2021 · Proteins

   RoseTTAFold from Baker lab matches AlphaFold 2 closely

   An academic three-track network reproduced near-AlphaFold accuracy and opened the field to design work. Source

10. Jul 15, 2021 · Proteins

    AlphaFold 2 paper and open code released

    Nature paper plus open source made accurate prediction available to every lab. Source

11. Jul 15, 2021 · Neuroscience

    Speech neuroprosthesis decodes words in paralyzed man

    Moses et al. decoded attempted speech to text in a person with anarthria. Source

12. Jun 23, 2021 · Astronomy

    DINGO speeds gravitational-wave inference to about a minute

    Neural posterior estimation matched standard codes on eight events while cutting runtime from about a day. Source

13. May 12, 2021 · Neuroscience

    Handwriting decoded from brain activity at 90 characters per minute

    Willett et al. used a recurrent network to turn imagined handwriting into text for a paralyzed participant. Source

14. Jan 27, 2021 · Imaging

    Mirai predicts breast cancer risk from mammograms

    Yala et al. validated a deep risk model across hospitals and countries. Source

15. Jan 20, 2021 · Physics

    Normalizing flows for lattice field theory introduced

    Normalizing-flow samplers sped up lattice field theory calculations. Source

1. Dec 14, 2020 · Imaging

   Cellpose: generalist cell segmentation

   Stringer et al. gave biologists a pretrained model that segments many cell types without retraining. Source

2. Nov 30, 2020 · Proteins

   AlphaFold 2 solves protein folding at CASP14

   Median GDT near 92 matched experimental accuracy and settled a 50-year grand challenge. Source

3. Nov 14, 2020 · Physics

   Fermilab Booster RL controller regulates magnet power

   A reinforcement-learned controller, trained on a surrogate, ran on FPGAs for accelerator control. Source

4. Oct 20, 2020 · Materials

   Open Catalyst 2020 (OC20) dataset released

   Meta and CMU released very large catalyst DFT dataset to drive ML for energy materials. Source

5. Sep 15, 2020 · Materials

   Matbench and ML-for-materials benchmarks mature (Matbench paper)

   Standardised benchmarks let materials ML models be compared fairly. Source

6. Sep 7, 2020 · Neuroscience

   Hemibrain connectome of the fly central brain published

   Scheffer et al. reconstructed about 25,000 neurons with machine-learning-assisted segmentation (eLife; preprint Jan 2020). Source

7. Aug 7, 2020 · Earth

   EQTransformer deep-learning earthquake detector published

   Deep learning pickers produced far richer earthquake catalogs and became standard seismology tools. Source

8. Jul 8, 2020 · Autonomous labs

   Mobile robotic chemist runs 688 experiments

   A free-roaming robot using Bayesian search found a better photocatalyst mixture in 8 days. Source

9. May 6, 2020 · Physics

   ATLAS runs first weakly supervised dijet resonance search

   ATLAS used weakly supervised ML on 139 fb-1 and found no significant excess. Source

10. Feb 2020 · Medicine

    Halicin: deep learning finds a new antibiotic

    Stokes et al. found a broad-spectrum antibiotic by screening 100 million molecules in silico. Source

11. Jan 30, 2020 · Medicine

    First AI-designed drug enters human trial (DSP-1181)

    Exscientia and Sumitomo Dainippon started Phase 1 for an AI-designed molecule after under 12 months of design. Source

12. Jan 1, 2020 · Imaging

    Google breast cancer AI outperforms radiologists

    McKinney et al. reported fewer false positives and negatives than readers in UK and US screening data. Source

1. Jul 15, 2019 · Medicine

   Clinical-grade pathology AI trained on 44,000 slides

   Campanella et al. showed weakly supervised slide-level cancer detection without pixel annotations. Source

2. May 3, 2019 · Neuroscience

   Neural network designs images that control deep cortical neurons

   Bashivan et al. used a model to drive V4 neurons beyond natural images, showing model-guided brain control. Source

3. Apr 26, 2019 · Physics

   Flow-based sampling attacks critical slowing down in lattice field theory

   Machine-learned flows sped up Monte Carlo sampling for lattice theories without needing existing samples. Source

4. Apr 24, 2019 · Neuroscience

   Speech synthesized directly from human cortical activity

   Anumanchipalli et al. decoded articulatory movements from cortex and generated intelligible speech. Source

5. Mar 4, 2019 · Imaging

   Deep learning virtual histological staining

   Rivenson et al. generated H&E-like stains from autofluorescence without chemical staining. Source

6. Nov 26, 2018 · Imaging

   CARE restores low-light fluorescence microscopy images

   Weigert et al. showed content-aware restoration enables imaging with far less light and faster acquisition. Source

7. Nov 22, 2018 · Earth

   LSTM networks beat benchmark at rainfall-runoff modelling

   LSTMs trained on 241 catchments beat a standard hydrologic model, opening deep learning in hydrology. Source

8. Sep 17, 2018 · Imaging

   Label-free prediction of 3D fluorescence from transmitted light

   Ounkomol et al. (Allen Institute) made virtual labeling of organelles practical. Source

9. Sep 10, 2018 · Astronomy

   Machine learning finds 72 hidden bursts from FRB 121102

   Breakthrough Listen's algorithm found 72 radio bursts missed in 2017 Green Bank data, a first for ML detection. Source

10. Aug 29, 2018 · Earth

    Deep learning predicts aftershock locations

    Neural net outperformed Coulomb stress for aftershock patterns, an early AI earthquake science result. Source

11. Aug 20, 2018 · Lab methods

    DeepLabCut brings markerless pose tracking to labs

    Mathis et al. made animal behavior tracking from video accessible with few labeled frames. Source

12. Aug 13, 2018 · Medicine

    DeepMind AI triages 50+ retinal diseases from OCT

    De Fauw et al. showed referral recommendations matching experts across many eye conditions. Source

13. Jul 18, 2018 · Chemistry

    Chemical space ML meets robot synthesis (Granda et al.)

    Nature 2018 work with ML-guided reaction discovery in an automated platform foreshadowed self-driving chemistry labs. Source

14. Jul 16, 2018 · Neuroscience

    Flood-filling networks automate brain tissue reconstruction

    Januszewski et al. made high-accuracy neuron segmentation from EM scalable, enabling modern connectomics. Source

15. Jul 2018 · Neuroscience

    Whole adult fly brain imaged at synaptic resolution (FAFB)

    Zheng et al. released the EM volume that FlyWire later segmented into a full connectome. Source

16. Apr 2018 · Imaging

    In silico labeling predicts fluorescence from brightfield

    Christiansen et al. trained nets to infer fluorescent labels from unlabeled images, the start of virtual staining. Source

17. Mar 29, 2018 · Chemistry

    Segler et al. neural retrosynthesis planning

    Deep neural nets plus tree search planned syntheses that chemists rated on par with literature routes. Source

18. Mar 8, 2018 · Earth

    PhaseNet deep network picks seismic arrivals

    A neural net picked P and S arrivals more accurately than older methods, starting the AI seismology wave. Source

19. Feb 13, 2018 · Medicine

    FDA authorizes Viz.ai AI stroke triage

    First FDA De Novo for AI that alerts clinicians to suspected large vessel occlusion on CT. Source

20. Jan 12, 2018 · Chemistry

    Gomez-Bombarelli: VAE continuous molecule design

    Autoencoder latent space allowed gradient-based optimisation of molecules, launching generative chemistry. Source

21. Dec 14, 2017 · Astronomy

    Kepler-90 eighth planet found with neural network

    Google and UT Austin network found a hidden exoplanet in Kepler data. Source

22. Nov 14, 2017 · Imaging

    CheXNet reaches radiologist-level pneumonia detection

    Rajpurkar et al. showed a 121-layer CNN matching radiologists on chest X-rays with a large public dataset. Source

23. Jun 26, 2017 · Chemistry

    SchNet and deep tensor networks for molecules

    Learned continuous-filter networks predicted molecular energies with near-DFT accuracy, a basis for MLIPs. Source

24. May 5, 2017 · Physics

    CaloGAN simulates calorimeter showers with GANs

    A GAN simulated 3D showers with speed-ups reported as high as 100,000 times. Source

25. Feb 28, 2017 · Astronomy

    Gravity Spy brings ML into LIGO glitch classification

    ML classifiers became part of LIGO glitch vetting and searches. Source

26. Feb 10, 2017 · Physics

    Neural networks identify phases of matter and learn quantum states

    Carleo and Troyer's neural quantum states opened ML for many-body physics. Source

27. Jan 25, 2017 · Medicine

    Deep network matches dermatologists on skin cancer

    Esteva et al. showed a CNN classifying skin lesions at dermatologist level, a widely cited Nature milestone. Source

28. Dec 30, 2016 · Astronomy

    Deep Filtering detects gravitational waves with neural nets

    Convolutional networks found binary black hole signals in noisy data far faster than matched filtering. Source

29. Dec 13, 2016 · Medicine

    Deep learning detects diabetic retinopathy at specialist level

    Gulshan et al. in JAMA validated a deep network on retinal photos, opening the era of clinical-grade medical imaging AI. Source

30. Nov 16, 2015 · Physics

    Jet-images paper brings deep learning to LHC jet tagging

    Early CNN jet-tagging paper that helped start deep learning for LHC jet classification; "standard" claim is not in the source. Source

31. May 18, 2015 · Imaging

    U-Net introduced for biomedical image segmentation

    U-Net became the default architecture for cell and medical image segmentation across labs. Source

32. Mar 24, 2015 · Astronomy

    Deep network learns Galaxy Zoo morphology labels

    A rotation-invariant CNN matched volunteer consensus on galaxy shapes with near-perfect accuracy on clear cases. Source

33. Mar 2015 · Early roots

    Eve robot scientist repositions drugs for neglected diseases

    Eve's automated screening validated cheaper drug development by repositioning compounds against neglected tropical disease targets. Source

34. May 8, 2014 · Neuroscience

    Deep nets predict neural responses in primate visual cortex

    Yamins and DiCarlo showed task-optimized networks match IT cortex, founding the NeuroAI modeling approach. Source

35. Jul 1, 2013 · Materials

    Materials Project launches open computed-materials database

    Open DFT database of inorganic materials became the training base for later ML materials models. Source

36. Jul 4, 2012 · Physics

    ATLAS and CMS announce Higgs boson discovery

    ATLAS and CMS announced the new particle at CERN on 4 July 2012. The ML role in the analyses is not sourced here. Source

37. May 16, 2012 · Neuroscience

    BrainGate participants steer a robotic arm to drink coffee

    Hochberg et al. showed reach-and-grasp control of a robot arm from decoded cortical signals. Source

1. Apr 3, 2009 · Early roots

   Eureqa distills natural laws from data

   Schmidt and Lipson's symbolic regression recovered laws of motion from raw measurements in Science. Source

2. Apr 3, 2009 · Early roots

   Adam, the first robot scientist to discover new knowledge

   Adam autonomously found yeast gene functions, with results confirmed by hand. Source

3. Apr 2, 2007 · Chemistry

   Behler-Parrinello neural network potentials

   First high-dimensional neural network potentials, seeding ML interatomic potentials for atomistic simulation. Source

4. Jul 2006 · Neuroscience

   BrainGate: tetraplegic man controls cursor by thought

   Hochberg et al. showed neural decoding of motor cortex activity could drive a computer in a human. Source

5. Jan 2004 · Early roots

   Robot scientist generates and tests hypotheses

   King et al. in Nature described a robot that formed yeast genomics hypotheses and ran experiments to test them. Source

6. Nov 21, 2003 · Proteins

   Baker lab designs Top7, a novel protein fold

   First de novo designed protein with a fold not seen in nature, proving computational design could work. Source

7. Feb 15, 2001 · Genomics

   Human genome draft sequences published

   The reference genome is the substrate for every genomics model that followed. Source

8. Jun 26, 1998 · Imaging

   FDA approves first computer-aided mammography detection (M1000)

   R2 ImageChecker became the first FDA-approved CAD device for reading mammograms. Source

9. 1994 · Proteins

   CASP launched to benchmark protein structure prediction

   A blind biennial contest gave the field its honest yardstick for 30 years. Source

10. Nov 12, 1986 · Neuroscience

    Complete C. elegans wiring diagram published

    White et al. mapped all 302 neurons by hand, the template every later connectome project followed. Source

11. 1979 · Early roots

    BACON.3 rediscovers physical laws from data

    Langley's BACON.3 rediscovered Kepler's third law and Ohm's law from numerical data, a template for data-driven discovery. Source

12. 1976 · Early roots

    Lenat's AM rediscovers math concepts

    The Automated Mathematician generated and explored concepts such as primes without human guidance. Source

13. 1976 · Medicine

    MYCIN expert system advises on infections

    MYCIN showed rule-based AI could match specialists at diagnosing bacterial infections and picking antibiotics. Source

14. 1971 · Proteins

    Protein Data Bank founded with 7 structures

    The open archive became the training data that made AlphaFold and later structure models possible. Source

15. 1964 · Early roots

    DENDRAL begins at Stanford

    First expert system to automate scientific reasoning: inferring molecular structures from mass spectra. Source

16. Mar 8, 1958 · Proteins

    Kendrew solves first protein 3D structure (myoglobin)

    X-ray crystallography revealed a protein's atomic structure, starting the structure data that later trained AI. Source

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